Goltz Syndrome is a condition in humans that adversely affects the skin - HSC - SSCE Biology - Question 15 - 2014 - Paper 1

To determine the inheritance pattern of Goltz Syndrome, we must first recognize that it is a dominant condition associated with a gene on the X chromosome.

A man with Goltz Syndrome must possess the genotype XY^G (where Y^G indicates the presence of the syndrome on the X chromosome) since males have one X chromosome. The woman, who does not have the syndrome, must have the genotype XX (indicating she has two normal X chromosomes).

When these two individuals have children, the possible combinations for their offspring can be examined:

1. Boy (XY): He inherits the Y chromosome from his father and one normal X chromosome from his mother. Therefore, he cannot inherit Goltz Syndrome, and he has a 0% chance of having the syndrome.

2. Girl (XX): She inherits one X chromosome from her father (which carries the condition) and one normal X chromosome from her mother. Thus, she will definitely inherit Goltz Syndrome and will display the phenotype associated with it.

In conclusion, the correct choice is that the girl has the syndrome, and the boy does not.