An extremely high concentration of carbon dioxide is undesirable in active muscle tissue because it will (A) increase the pH - HSC - SSCE Biology - Question 6 - 2015 - Paper 1

An extremely high concentration of carbon dioxide can lead to a lower pH in muscle tissue due to the formation of carbonic acid. This decline in pH can cause enzymes to denature, disrupting their functionality. Enzymes are sensitive to pH changes; their active sites can be altered, rendering them less effective or ineffective, which is detrimental for muscle metabolism and energy production during periods of high activity.