Goltz Syndrome is a condition in humans that adversely affects the skin - HSC - SSCE Biology - Question 15 - 2014 - Paper 1

To understand the inheritance of Goltz Syndrome, first recognize that it is a dominant trait linked to the X chromosome. A man with Goltz Syndrome has the genotype X^G Y (where X^G represents the X chromosome with the Goltz allele) and the woman, being unaffected, has the genotype X^X X^X (two normal X chromosomes).

When these parents have children:

• The son inherits an X chromosome from his mother and a Y from his father, giving him the genotype X^X Y, and he will not have the syndrome because he receives the normal X from his mother.
• The daughter inherits one X chromosome from each parent, resulting in X^G X^X. Since she inherits the affected X^G from her father, she will express the syndrome.

Thus, the only appropriate choice is (B): The girl has the syndrome and the boy does not.