Bevacizumab is a humanised monoclonal antibody that is used to treat several different cancers - VCE - SSCE Biology - Question 27 - 2023 - Paper 1
Question 27
Bevacizumab is a humanised monoclonal antibody that is used to treat several different cancers. Humanising involves removing part of the constant region of a mouse m... show full transcript
Worked Solution & Example Answer:Bevacizumab is a humanised monoclonal antibody that is used to treat several different cancers - VCE - SSCE Biology - Question 27 - 2023 - Paper 1
Step 1
reduce the chances of an immune response against bevacizumab.
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Answer
The humanisation of monoclonal antibodies like bevacizumab mitigates the risk of the human immune system recognizing the antibody as foreign. By incorporating human components, the antibody is less likely to provoke an immune response, allowing for more effective and longer-lasting treatment. This is crucial when antibodies are used repetitively in a clinical setting.