The receptors that are responsible for detecting GH in liver cells and fat cells are located - in the cytosol - VCE - SSCE Biology - Question 13 - 2021 - Paper 1

The receptors responsible for detecting Growth Hormone (GH) are primarily located on the plasma membrane of the target cells. This is because GH is a protein hormone and, therefore, cannot cross the lipid bilayer of the cell membrane. Instead, it binds to its receptors on the membrane, initiating a signaling cascade that eventually leads to the desired physiological effects.