During antibody-mediated hypersensitivity
A - VCE - SSCE Biology - Question 23 - 2009 - Paper 1
Question 23
During antibody-mediated hypersensitivity
A. blood vessels constrict.
B. B cells release histamine.
C. macrophages destroy T cells.
D. IgE antibodies attach to mast ... show full transcript
Worked Solution & Example Answer:During antibody-mediated hypersensitivity
A - VCE - SSCE Biology - Question 23 - 2009 - Paper 1
Step 1
A. blood vessels constrict.
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Answer
This statement is not accurate during antibody-mediated hypersensitivity. While blood vessel constriction may occur in certain types of allergic reactions, it is not a primary feature of antibody-mediated responses.
Step 2
B. B cells release histamine.
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Answer
This statement is incorrect. B cells do not release histamine. Instead, they produce antibodies, specifically IgE in the case of hypersensitivity.
Step 3
C. macrophages destroy T cells.
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This is not true for antibody-mediated hypersensitivity. Macrophages have different roles and do not primarily destroy T cells in this context.
Step 4
D. IgE antibodies attach to mast cells.
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Answer
This is the correct statement. In antibody-mediated hypersensitivity, IgE antibodies attach to mast cells, which leads to their activation and the release of histamine and other inflammatory mediators.