the degranulation process shown in the diagram above, an intracellular substance (Z) leaves the cell - VCE - SSCE Biology - Question 24 - 2020 - Paper 1

In the context of the degranulation process, the intracellular substance (Z) that typically leaves the cell is histamine. Histamine is released by mast cells and basophils during immune responses, particularly in allergic reactions. It plays a crucial role in the inflammatory process by increasing the permeability of blood vessels, allowing immune cells to access affected tissues.