Vibrio cholerae produces a toxin that binds to a plasma membrane receptor on intestinal cells of the host - VCE - SSCE Biology - Question 12 - 2011 - Paper 1
Question 12
Vibrio cholerae produces a toxin that binds to a plasma membrane receptor on intestinal cells of the host. The toxin permanently activates the G protein in target ce... show full transcript
Worked Solution & Example Answer:Vibrio cholerae produces a toxin that binds to a plasma membrane receptor on intestinal cells of the host - VCE - SSCE Biology - Question 12 - 2011 - Paper 1
Step 1
A. disrupts normal signal transduction in the cell.
96%
114 rated
Only available for registered users.
Sign up now to view full answer, or log in if you already have an account!
Answer
The V. cholerae toxin primarily disrupts normal signal transduction within the cell. By permanently activating the G protein, it interferes with the usual signaling pathways, leading to the rapid loss of water from the cells, which results in severe dehydration. This mechanism classifies it as a pathogenic factor that impacts cellular communication.
Step 2
B. is an example of a second messenger molecule.
99%
104 rated
Only available for registered users.
Sign up now to view full answer, or log in if you already have an account!
Answer
This statement is inaccurate. The V. cholerae toxin itself is not a second messenger. Instead, it acts on the G protein, which is part of the signaling cascade that could include second messenger molecules, but does not fit the definition of one.
Step 3
C. is a lipid-soluble molecule.
96%
101 rated
Only available for registered users.
Sign up now to view full answer, or log in if you already have an account!
Answer
The cholera toxin is not lipid-soluble; rather, it is a protein that functions in the aqueous environment of the intestine. Therefore, it does not match the characteristics of lipid-soluble molecules which can easily pass through cell membranes.
Step 4
D. acts as a neurohormone.
98%
120 rated
Only available for registered users.
Sign up now to view full answer, or log in if you already have an account!
Answer
This statement is also incorrect. While the cholera toxin has systemic effects, it does not function as a neurohormone. Neurohormones are typically released by neurons and have targeted actions, whereas the cholera toxin primarily induces its effects through direct action on intestinal cells.