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Vibrio cholerae produces a toxin that binds to a plasma membrane receptor on intestinal cells of the host - VCE - SSCE Biology - Question 12 - 2011 - Paper 1

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Vibrio cholerae produces a toxin that binds to a plasma membrane receptor on intestinal cells of the host. The toxin permanently activates the G protein in target ce... show full transcript

Worked Solution & Example Answer:Vibrio cholerae produces a toxin that binds to a plasma membrane receptor on intestinal cells of the host - VCE - SSCE Biology - Question 12 - 2011 - Paper 1

Step 1

A. disrupts normal signal transduction in the cell.

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Answer

The V. cholerae toxin primarily disrupts normal signal transduction within the cell. By permanently activating the G protein, it interferes with the usual signaling pathways, leading to the rapid loss of water from the cells, which results in severe dehydration. This mechanism classifies it as a pathogenic factor that impacts cellular communication.

Step 2

B. is an example of a second messenger molecule.

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This statement is inaccurate. The V. cholerae toxin itself is not a second messenger. Instead, it acts on the G protein, which is part of the signaling cascade that could include second messenger molecules, but does not fit the definition of one.

Step 3

C. is a lipid-soluble molecule.

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The cholera toxin is not lipid-soluble; rather, it is a protein that functions in the aqueous environment of the intestine. Therefore, it does not match the characteristics of lipid-soluble molecules which can easily pass through cell membranes.

Step 4

D. acts as a neurohormone.

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This statement is also incorrect. While the cholera toxin has systemic effects, it does not function as a neurohormone. Neurohormones are typically released by neurons and have targeted actions, whereas the cholera toxin primarily induces its effects through direct action on intestinal cells.

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