The function of a protein is dependent on its three-dimensional structure - VCE - SSCE Chemistry - Question 15 - 2006 - Paper 1
Question 15
The function of a protein is dependent on its three-dimensional structure. This structure can be disrupted, denaturing the protein.
Which of the following changes c... show full transcript
Worked Solution & Example Answer:The function of a protein is dependent on its three-dimensional structure - VCE - SSCE Chemistry - Question 15 - 2006 - Paper 1
Step 1
I the addition of a strong acid
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Answer
The addition of a strong acid can lead to denaturation by altering the pH of the environment in which the protein exists. This change in pH can disrupt the ionic and hydrogen bonds that help maintain the protein's three-dimensional structure, making it more likely to unfold or denature.
Step 2
II the addition of a strong base
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Answer
Similarly, the addition of a strong base can also cause denaturation. Like strong acids, strong bases also alter the pH and can disrupt the bonds that stabilize the protein's structure, leading to unfolding.
Step 3
III a significant increase in temperature
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A significant increase in temperature can lead to denaturation as well. High temperatures can cause proteins to gain kinetic energy, resulting in increased molecular motion. This can disrupt the non-covalent interactions and allow the protein to lose its specific shape.
Step 4
Conclusion
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Answer
Based on the explanations above, all three factors - the addition of a strong acid, a strong base, and a significant increase in temperature - can contribute to the denaturation of proteins. Therefore, the correct answer is D: I, II and III.
