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In response to a pain stimulus, the brain produces small polypeptide molecules called enkephalins - VCE - SSCE Chemistry - Question 16 - 2009 - Paper 1

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In response to a pain stimulus, the brain produces small polypeptide molecules called enkephalins. These molecules block the transmission of pain through the central... show full transcript

Worked Solution & Example Answer:In response to a pain stimulus, the brain produces small polypeptide molecules called enkephalins - VCE - SSCE Chemistry - Question 16 - 2009 - Paper 1

Step 1

Identify the functional groups

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Answer

To solve this problem, we need to identify the number of each functional group present in the polypeptide methionine enkephalin, which consists of the amino acid sequence Tyr – Gly – Gly – Phe – Met.

  1. Amine Group (–NH₂): The first amino acid, Tyrosine (Tyr), contains one amine group at the beginning of the chain; thus, there is 1 amine group.
  2. Carboxylic Acid Group (–COOH): Each amino acid has a carboxyl group. Since there are 5 amino acids (Tyr, Gly, Gly, Phe, Met), there are 5 carboxylic acid groups in total.
  3. Amide Group (–CONH): In this case, the connection between the amino acids involves amide (peptide) bonds. There is one amide bond for each peptide link minus one for the terminal amino acid at the end. Therefore, with 5 amino acids, there are 4 amide groups.

Step 2

Total functional groups in the polypeptide

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Answer

From the analysis, we conclude:

  • Amine groups: 1
  • Carboxylic acid groups: 5
  • Amide groups: 4

This aligns with option C: 1 5 4, which correctly represents the number of functional groups present in methionine enkephalin.

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