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Question 5
Describe the role of glucagon in gluconeogenesis. Do not include in your answer details on the second messenger model of glucagon action.
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Answer
Glucagon plays a crucial role in gluconeogenesis, which is the synthesis of glucose from non-carbohydrate precursors. When blood sugar levels are low, glucagon is secreted by the alpha cells of the pancreas. It binds to specific receptors on target cells, which activates enzymes responsible for converting amino acids and glycerol into glucose, thereby increasing blood glucose levels. Importantly, glucagon helps to stimulate the processes that release stored glucose into the bloodstream, maintaining energy homeostasis.
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