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Figure 1 shows all the chromosomes present in one human cell during mitosis - AQA - A-Level Biology - Question 1 - 2018 - Paper 1

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Figure 1 shows all the chromosomes present in one human cell during mitosis. A scientist stained and photographed the chromosomes. In Figure 2, the scientist has... show full transcript

Worked Solution & Example Answer:Figure 1 shows all the chromosomes present in one human cell during mitosis - AQA - A-Level Biology - Question 1 - 2018 - Paper 1

Step 1

Give two pieces of evidence from Figure 1 that this cell was undergoing mitosis. Explain your answers.

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Answer

  1. The individual chromosomes are visible because they have condensed. This suggests that the cell is preparing for division as chromosomes condense to become more distinct during mitosis.

  2. Each chromosome is made up of two chromatids because DNA has replicated. This is indicative of the mitotic phase where replication has occurred prior to cell division.

Step 2

Tick (✓) one box that gives the name of the stage of mitosis shown in Figure 1.

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Answer

Prophase

Step 3

Suggest how this procedure moved the chromosomes apart.

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Answer

Water moves into the cells/cytoplasm by osmosis, leading to an increase in cell volume. This expansion pushes the chromosomes apart, reducing overlapping and allowing clearer visibility under the microscope.

Step 4

Suggest one way the structure of the chromosome could differ along its length to result in the stain binding more in some areas.

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Answer

The differences in base sequences of DNA or variations in histone interaction could lead to differing degrees of condensation, causing some areas to attract the stain more than others.

Step 5

What is a homologous pair of chromosomes?

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Answer

A homologous pair consists of two chromosomes that carry the same genes at the same loci, even though they may have different alleles.

Step 6

Give two ways in which the arrangement of prokaryotic DNA is different from the arrangement of the human DNA in Figure 1.

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Answer

  1. Prokaryotic DNA is circular as opposed to linear in eukaryotes.

  2. Prokaryotic DNA is not associated with proteins/histones, whereas human DNA is tightly regulated with histone proteins.

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