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What statistical test could the scientists use to determine whether there was a significant relationship between the amount of CD20 on the surface of B cells and the percentage of B cells destroyed by Rituximab? Name of test ___________ Reason _________ From these data, what can you conclude about the effectiveness of Rituximab in treating patients with CLL? Do not include considerations of statistical analyses in your answer - AQA - A-Level Biology - Question 2 - 2018 - Paper 3

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What-statistical-test-could-the-scientists-use-to-determine-whether-there-was-a-significant-relationship-between-the-amount-of-CD20-on-the-surface-of-B-cells-and-the-percentage-of-B-cells-destroyed-by-Rituximab?--Name-of-test-___________--Reason-_________--From-these-data,-what-can-you-conclude-about-the-effectiveness-of-Rituximab-in-treating-patients-with-CLL?--Do-not-include-considerations-of-statistical-analyses-in-your-answer-AQA-A-Level Biology-Question 2-2018-Paper 3.png

What statistical test could the scientists use to determine whether there was a significant relationship between the amount of CD20 on the surface of B cells and the... show full transcript

Worked Solution & Example Answer:What statistical test could the scientists use to determine whether there was a significant relationship between the amount of CD20 on the surface of B cells and the percentage of B cells destroyed by Rituximab? Name of test ___________ Reason _________ From these data, what can you conclude about the effectiveness of Rituximab in treating patients with CLL? Do not include considerations of statistical analyses in your answer - AQA - A-Level Biology - Question 2 - 2018 - Paper 3

Step 1

Name of test

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Answer

The appropriate statistical test that could be used is the Pearson correlation coefficient.

Step 2

Reason

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Answer

This test is suitable as it measures the strength and direction of the linear relationship between two continuous variables: the amount of CD20 on the surface of B cells and the percentage of B cells destroyed by Rituximab.

Step 3

From these data, what can you conclude about the effectiveness of Rituximab in treating patients with CLL?

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Answer

The data suggests that Rituximab is more effective in treating patients with higher amounts of CD20 on B cells, as it leads to a greater percentage of B cell destruction. However, the variability among patients indicates that while higher CD20 levels correlate with better treatment outcomes, it does not guarantee complete effectiveness, as not all B cells are destroyed.

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