What statistical test could the scientists use to determine whether there was a significant relationship between the amount of CD20 on the surface of B cells and the percentage of B cells destroyed by Rituximab?
Name of test ___________
Reason _________
From these data, what can you conclude about the effectiveness of Rituximab in treating patients with CLL?
Do not include considerations of statistical analyses in your answer - AQA - A-Level Biology - Question 2 - 2018 - Paper 3
Question 2
What statistical test could the scientists use to determine whether there was a significant relationship between the amount of CD20 on the surface of B cells and the... show full transcript
Worked Solution & Example Answer:What statistical test could the scientists use to determine whether there was a significant relationship between the amount of CD20 on the surface of B cells and the percentage of B cells destroyed by Rituximab?
Name of test ___________
Reason _________
From these data, what can you conclude about the effectiveness of Rituximab in treating patients with CLL?
Do not include considerations of statistical analyses in your answer - AQA - A-Level Biology - Question 2 - 2018 - Paper 3
Step 1
Name of test
96%
114 rated
Only available for registered users.
Sign up now to view full answer, or log in if you already have an account!
Answer
The appropriate statistical test that could be used is the Pearson correlation coefficient.
Step 2
Reason
99%
104 rated
Only available for registered users.
Sign up now to view full answer, or log in if you already have an account!
Answer
This test is suitable as it measures the strength and direction of the linear relationship between two continuous variables: the amount of CD20 on the surface of B cells and the percentage of B cells destroyed by Rituximab.
Step 3
From these data, what can you conclude about the effectiveness of Rituximab in treating patients with CLL?
96%
101 rated
Only available for registered users.
Sign up now to view full answer, or log in if you already have an account!
Answer
The data suggests that Rituximab is more effective in treating patients with higher amounts of CD20 on B cells, as it leads to a greater percentage of B cell destruction. However, the variability among patients indicates that while higher CD20 levels correlate with better treatment outcomes, it does not guarantee complete effectiveness, as not all B cells are destroyed.