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Give two reasons why transmission across a cholinergic synapse is unidirectional - AQA - A-Level Biology - Question 7 - 2022 - Paper 2

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Give two reasons why transmission across a cholinergic synapse is unidirectional. 1 2

Worked Solution & Example Answer:Give two reasons why transmission across a cholinergic synapse is unidirectional - AQA - A-Level Biology - Question 7 - 2022 - Paper 2

Step 1

1. (Only) the presynaptic neurone/knob/membrane releases/has neurotransmitter/acetylcholine:

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Answer

Transmission is unidirectional because only the presynaptic neuron releases acetylcholine, which binds to receptors on the postsynaptic membrane.

Step 2

2. (Only) the postsynaptic neurone/membrane has receptors:

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Answer

The postsynaptic neurone has specific receptors for acetylcholine. Therefore, any neurotransmitter released can only influence the postsynaptic neurone.

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