The secretion of osteocalcin (in an inactive form) by osteoblasts is controlled by positive feedback - AQA - A-Level Biology - Question 1 - 2018 - Paper 3
Question 1
The secretion of osteocalcin (in an inactive form) by osteoblasts is controlled by positive feedback.
Use information from Figure 1 to explain why this is positive ... show full transcript
Worked Solution & Example Answer:The secretion of osteocalcin (in an inactive form) by osteoblasts is controlled by positive feedback - AQA - A-Level Biology - Question 1 - 2018 - Paper 3
Step 1
Osteocalcin causes more release of insulin
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Answer
Osteocalcin, when secreted, triggers an increase in the release of insulin from the beta cells in the pancreas. This action creates a positive feedback loop, as higher levels of osteocalcin lead to even more insulin secretion.
Step 2
More insulin causes more active osteocalcin
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Answer
As the concentration of insulin increases, it stimulates osteoblasts further. This results in more osteocalcin being produced, particularly in its active form, enhancing the cycle of feedback.
