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This question is about inheritance - AQA - GCSE Biology Combined Science - Question 5 - 2020 - Paper 2

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This question is about inheritance. Humans have 23 pairs of chromosomes in each body cell. One pair of chromosomes determines sex. Complete Figure 5. Figure 5 ... show full transcript

Worked Solution & Example Answer:This question is about inheritance - AQA - GCSE Biology Combined Science - Question 5 - 2020 - Paper 2

Step 1

Complete Figure 5

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Answer

To complete Figure 5, the possible male and female gametes should be placed in the square:

     Female

           X                     X

_________________

     Male

           Y                     Y

This shows the potential offspring genotypes.

Step 2

In some families all children are the same sex. Give the reason why.

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Answer

In some families, all children can be the same sex due to the random nature of which sperm cells (carrying either X or Y chromosomes) fertilize the egg. Each child has a 50% chance of being male or female, but it's possible, by chance, for all children to be of the same sex.

Step 3

Draw a Punnett square diagram to find the probability that their next child will have CF.

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Answer

The Punnett square for the scenario where both parents are carriers (Tt) is as follows:

   T           t
___________________
T |  TT       |   Tt
---------------------
T |  Tt      |   tt

In this case, TT = normal, Tt = carrier, and tt = affected by CF. The probabilities are:

  • TT: 25%
  • Tt: 50%
  • tt: 25%

Thus, the probability of the next child having CF (tt) is 25%.

Step 4

Suggest three reasons for choosing Method 1 instead of Method 2.

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Answer

  • Does not need IVF which is stressful/invasive.
  • Higher chance of successful pregnancy as risk of miscarriage is low compared to the 30% success rate of IVF.
  • The test is freely available and can be carried out even if the mother is pregnant.

Step 5

Suggest one advantage of Method 2.

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Answer

One advantage of Method 2 is that it ensures that only embryos without CF are implanted in the woman's uterus, thereby reducing the risk of having a child with CF.

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