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Question 10
10 (a) One gene can have several different alleles. Explain why these alleles can produce proteins with different structures. (b) Monoclonal antibodies are proteins... show full transcript
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Alleles are different versions of a gene that result from mutations in the DNA sequence. Each allele may have a variation in nucleotide sequences, leading to the production of distinct mRNA strands with unique sequences.
DNA Sequence Variation: Different alleles possess variations in their DNA sequences, which may result in the production of different mRNA molecules.
mRNA Transcription: When genes are transcribed, these alleles produce mRNA that has different triplet sequences. This can affect the codons read during translation.
Amino Acid Coding: Each unique mRNA sequence codes for potentially different amino acids or orders of amino acids, which ultimately influences the folding of proteins.
Protein Folding: The order of amino acids determines how a protein folds, and this can lead to variations in the structure and function of the proteins produced by different alleles.
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