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10 (a) One gene can have several different alleles - Edexcel - GCSE Biology - Question 10 - 2021 - Paper 1

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10 (a) One gene can have several different alleles. Explain why these alleles can produce proteins with different structures. (b) Monoclonal antibodies are proteins... show full transcript

Worked Solution & Example Answer:10 (a) One gene can have several different alleles - Edexcel - GCSE Biology - Question 10 - 2021 - Paper 1

Step 1

Explain why these alleles can produce proteins with different structures.

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Answer

Alleles are different versions of a gene that result from mutations in the DNA sequence. Each allele may have a variation in nucleotide sequences, leading to the production of distinct mRNA strands with unique sequences.

  1. DNA Sequence Variation: Different alleles possess variations in their DNA sequences, which may result in the production of different mRNA molecules.

  2. mRNA Transcription: When genes are transcribed, these alleles produce mRNA that has different triplet sequences. This can affect the codons read during translation.

  3. Amino Acid Coding: Each unique mRNA sequence codes for potentially different amino acids or orders of amino acids, which ultimately influences the folding of proteins.

  4. Protein Folding: The order of amino acids determines how a protein folds, and this can lead to variations in the structure and function of the proteins produced by different alleles.

Step 2

Which type of cell is added to the B lymphocytes to produce the hybridoma?

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Answer

C. cancer cell

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