Scottish Highers Biology Problem Solving: Cystic fibrosis in humans is cau

Question

Cystic fibrosis in humans is caused by mutations in a gene that reduces chloride transport across the cell membrane.

An investigation was carried out to determine the effectiveness of two drugs, P and Q, on improving chloride transport in individuals with cystic fibrosis. Individuals with different mutations, A, B and both A and B, were treated as follows.

- No drugs
- Drug P alone
- Drug Q alone
- Drug P and drug Q combined

Chloride transport across cell membranes was measured and compared to the chloride transport in a control group with no mutations in the gene.

The results are shown in the graph.

(a) State the purpose of including a control group in this investigation.

(b) Identify the treatment and mutation for which the drug(s) had no effect.

Treatment _______________________________

Mutation _______________________________

(c) State how the graph shows that each treatment was carried out on more than one individual with each mutation.

_______________________________________

(d) State the term used to describe the selection of drugs to treat individuals based on their genomic sequence.

Cystic fibrosis in humans is caused by mutations in a gene that reduces chloride transport across the cell membrane - Scottish Highers Biology - Question 6 - 2019

Worked Solution & Example Answer:Cystic fibrosis in humans is caused by mutations in a gene that reduces chloride transport across the cell membrane - Scottish Highers Biology - Question 6 - 2019

State the purpose of including a control group in this investigation.

Identify the treatment and mutation for which the drug(s) had no effect.

State how the graph shows that each treatment was carried out on more than one individual with each mutation.

State the term used to describe the selection of drugs to treat individuals based on their genomic sequence.

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