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The table shows the positions of bases in the mRNA codons for specific amino acids - Scottish Highers Human Biology - Question 5 - 2018

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The table shows the positions of bases in the mRNA codons for specific amino acids. First position Second position Third position U phenylalanine tyrosine... show full transcript

Worked Solution & Example Answer:The table shows the positions of bases in the mRNA codons for specific amino acids - Scottish Highers Human Biology - Question 5 - 2018

Step 1

Which of the following mutations in a section of mRNA would result in the production of a shortened protein?

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Answer

To determine which mutation results in a shortened protein, we should analyze the mutated mRNA codons given in the options.

  1. Original Codons: AUG GGC CAU

    • AUG: Methionine (start)
    • GGC: Glycine
    • CAU: Histidine
  2. Mutated Options:

    • A: AUG GCU CAU - GCU codes for Alanine.
    • B: CAG UAG UGG - UAG is a stop codon (this would shorten the protein).
    • C: CAG UAG UGG - Same as Option B.
    • D: GUC AAC UGG - GUC codes for Valine and does not introduce a stop codon.
    • E: GUC AAG UGG - AAG codes for Lysine, no stop codon.

From this analysis, the correct choice is B, as it includes a stop codon that would lead to the premature termination of protein synthesis.

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