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Amino Acids & the Peptide Bond Simplified Revision Notes

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1.3.1 Amino Acids & the Peptide Bond

Proteins are made up of smaller units called amino acids, which are the monomers of proteins.

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Each amino acid contains the following key components:

  • An amino group (NHâ‚‚)
  • A carboxyl group (-COOH)
  • A variable R group, which is a side chain that differs in each amino acid and determines its specific properties.
infoNote

There are 20 different amino acids, each with a unique R group. These amino acids are joined together by peptide bonds in a process called condensation. During this reaction, a molecule of water is released as two amino acids bond together.

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Formation of the Peptide Bond:

  • The carboxyl group of one amino acid reacts with the amino group of another, forming a peptide bond.
  • This bond links the amino acids together, creating a dipeptide (two amino acids) or a polypeptide (three or more amino acids).
  • As more amino acids join, the chain lengthens, eventually forming a protein. Proteins are essential macromolecules that play a wide range of functions in living organisms, from enzymes to structural components. Understanding the basic structure of amino acids and peptide bonds is key to grasping how proteins are built and function.
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