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Structure of Eukaryotic Cells Simplified Revision Notes

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2.1.2 Structure of Eukaryotic Cells

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Eukaryotic cells are highly organised structures that contain a nucleus and membrane-bound organelles, allowing them to perform specialised functions. The detailed organisation of these cells is referred to as the ultrastructure, visible using advanced microscopy techniques.

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Key Organelles in Eukaryotic Cells:

  1. Nucleus:
  • Surrounded by a double membrane (nuclear envelope) with ~3000 nuclear pores, allowing molecules to move in and out.
  • Contains:
  • Chromatin: DNA and associated proteins.
  • Nucleolus: Produces ribosomes.
  • Nucleoplasm: Jelly-like substance that forms the bulk of the nucleus.
  1. Rough Endoplasmic Reticulum (RER):
  • A network of flattened sacs enclosed by a membrane.
  • Surface is studded with ribosomes, giving it a "rough" appearance.
  • Function: Folds and processes proteins synthesised by the ribosomes.
  1. Smooth Endoplasmic Reticulum (SER):
  • A network of membrane-bound sacs without ribosomes.
  • Function: Synthesises and processes lipids.
  1. Golgi Apparatus:
  • A stack of fluid-filled, flattened, curved sacs, with vesicles at the edges.
  • Function:
  • Modifies, packages, and transports proteins and lipids.
  • Produces lysosomes.
  1. Mitochondria:
  • Oval-shaped, surrounded by a double membrane.
  • The inner membrane is folded into cristae, which increase the surface area for respiration.
  • The internal space, called the matrix, contains enzymes needed for aerobic respiration to produce ATP.
  1. Ribosomes:
  • Made of two subunits (large and small).
  • Found either free in the cytoplasm or attached to the RER.
  • Function: Site of protein synthesis.
  1. Lysosomes:
  • Small vesicles bound by a single membrane, containing digestive enzymes.
  • Function: Break down waste materials, old organelles, and pathogens.
  1. Centrioles:
  • Hollow cylinders made of microtubules, arranged at right angles to each other.
  • Function: Organise the spindle fibres during cell division.
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Exam Tip:

  • Learn to draw and label the ultrastructure of a eukaryotic cell, including all organelles.
  • Relate the structure of each organelle to its specific function, e.g., cristae in mitochondria increase surface area for ATP production.
  • Highlight the differences between RER and SER for clarity.
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