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Protein Synthesis Simplified Revision Notes

Revision notes with simplified explanations to understand Protein Synthesis quickly and effectively.

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Protein Synthesis

  • Genes control cells by producing enzymes.
  • Enzymes are proteins.
  • To make the correct protein, amino acids must be assembled in the correct order in ribosomes.
  • This process involves:
    1. The genetic code in DNA being transcribed to mRNA.
    2. The code on mRNA being translated into the correct sequence of amino acids.

Steps of Protein Synthesis:

  1. Initiation
  2. Transcription
  3. Translation
infoNote

Transcription occurs in the nucleus. Translation occurs in the ribosomes.

1. Initiation:

The part of the DNA double helix that codes for the protein unwinds.

2. Transcription:

infoNote

Transcription is the making of mRNA using a DNA template.

  • Occurs in the nucleus.
  • Complementary RNA bases attach to the exposed DNA bases.
  • The RNA bases are joined together by RNA polymerase to form messenger RNA (mRNA).
  • mRNA moves from the nucleus to the cytoplasm.
  • This process copies information from DNA to RNA.

3. Translation:

infoNote

Translation uses the mRNA code to form protein.

  • Occurs in the ribosome.
  • mRNA attaches to the ribosome, which is made of ribosomal RNA (rRNA).
  • Transfer RNA (tRNA) molecules in the cytoplasm are attracted to the mRNA.
  • Each tRNA carries a specific amino acid.
  • Triplets (codons) on the mRNA strand attract complementary triplets (anti-codons) on the tRNA molecules.
  • The amino acids are detached from their tRNA molecules and bonded together to form the new protein.
  • The protein folds into the correct 3D shape to allow it to function properly.
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