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Microorganisms in Industrial Fermentations Simplified Revision Notes

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Microorganisms in Industrial Fermentations

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Bioprocessing: the use of enzyme-controlled reactions to make a product.

Key Points about Industrial Fermentations:

  • Micro-organisms Used:
    • The main micro-organisms used are bacteria and fungi, especially yeast.
    • Although plant and animal cells can be used, micro-organisms are preferred due to their efficiency.
  • Fermentation:
    • In industry, fermentation refers to the production of useful products by micro-organisms, with or without oxygen.
  • Bioreactors:
    • Industrial fermentations are carried out in bioreactors (large vessels designed for fermentation).
    • To ensure the product is properly formed, specific conditions must be maintained:
    1. Correct nutrients and micro-organisms must be used.
    2. Temperature and pH must be kept at suitable levels.
    3. Oxygen may or may not be required, depending on the process.
    4. A sterile environment is essential to prevent contamination.
    5. The mixture is usually stirred or agitated to ensure even distribution of nutrients and conditions.

Micro-organisms Used in Bioprocessing:

  1. Yeast:
  • Used to produce beer and wine through alcohol fermentation.
  • Produces carbon dioxide to help dough rise in bread making.
  1. Bacteria and Yeasts (Traditional Products):
  • In the past, bacteria and yeasts were used to produce:
  • Yoghurt
  • Cheese
  • Vinegar
  • Soy sauce
  • Antibiotics
  1. Genetically Altered Micro-organisms:
  • More recently, bacteria, yeasts, and fungi have been genetically modified to produce a wide variety of products, including:
  • Solvents
  • Amino acids
  • Vitamins
  • Drugs
  • Food additives
  • Enzymes to break down stains (e.g., in detergents).
  • Fuel such as biogas.
  • Flavourings for food products.
  1. Immobilised Micro-organisms:
  • Immobilised E. coli is used in water treatment to detoxify sewage in waste water.

Importance of Micro-organisms in Industrial Fermentations:

  1. Micro-organisms play a key role in producing a wide range of products used in food, medicine, and industry.
  2. Advances in genetic engineering have expanded the range of products that can be made using micro-organisms.
  3. They are cost-effective, efficient, and environmentally friendly.
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